Posted February 2020
Pharmacogenomics, ie, the study of how an individual’s genomic profile influences his or her response to drugs, has emerged as a clinical tool to optimize drug therapy.
Certain variants in some genes increase the risk of severe, li…
Posted July 2022
Pharmacogenomic testing in children with complex medical histories can help predict and prevent adverse drug reactions, improve adherence and salvage drugs with high toxicity.
The tests yield actionable results in most cases, acording to Shannon…
One of the primary interventions in the treatment and prevention of disease is the use of medications. However, the unintended consequences from the use of medication regimens that are not optimized for the patient have been estimated to co…
Posted October 2014
Although the field of pharmacogenetics has existed for decades, the implementation of pharmacogenetic testing in clinical care has been slow. There are numerous publications, describing the barriers to clinical implementation of pharmacogenet…
Posted July 2022.
When deciding to prescribe a medicine to alleviate depression, doctors and patients face a fraught process of trial and error. After the initial clinical evaluation, a doctor’s first choice of antidepressant has a 50–50 chance of working, which …